Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Medicine & Life Sciences

• Organoids 100%
• Cystic Fibrosis Transmembrane Conductance Regulator 95%
• Colforsin 83%
• Cystic Fibrosis 74%
• In Vitro Techniques 33%
• Pharmaceutical Preparations 31%
• calcein green 16%
• Mutation 14%
• Basement Membrane 8%
• Microscopy 7%
• Costs and Cost Analysis 5%
• Biopsy 5%
• Therapeutics 1%

Engineering & Materials Science

• Assays 88%
• Swelling 84%
• Modulators 51%
• Basement Membrane 47%
• Biopsy 33%
• Microscopic examination 27%
• Costs 9%

Chemical Compounds

• Drug 40%
• Mutation 24%
• Rectal 14%
• Calcein 13%
• Conductance 9%
• Heterogeneity 8%
• Plate Like Crystal 7%
• Green 6%
• Surface 3%