Hippocampal activity in working memory tasks: sparse, yet relevant

TY - JOUR

T1 - Hippocampal activity in working memory tasks

T2 - sparse, yet relevant

AU - Peters, Judith C

AU - Reithler, Joel

PY - 2022/10/9

Y1 - 2022/10/9

N2 - Recent studies suggest the hippocampus is involved in working memory (WM). Slotnick (this issue) critically reviewed relevant fMRI findings and concludes WM 'does not activate the hippocampus.' We extend Slotnick's review by discussing observations from human intracranial and lesion research. These studies do suggest hippocampal contributions to WM (beyond novelty encoding), which however are difficult to capture with conventional fMRI. Still, the advent of new fMRI techniques combined with a stronger emphasis on shared hippocampal mechanisms across short- and long-term memory pave an exciting path forward.

AB - Recent studies suggest the hippocampus is involved in working memory (WM). Slotnick (this issue) critically reviewed relevant fMRI findings and concludes WM 'does not activate the hippocampus.' We extend Slotnick's review by discussing observations from human intracranial and lesion research. These studies do suggest hippocampal contributions to WM (beyond novelty encoding), which however are difficult to capture with conventional fMRI. Still, the advent of new fMRI techniques combined with a stronger emphasis on shared hippocampal mechanisms across short- and long-term memory pave an exciting path forward.

U2 - 10.1080/17588928.2022.2131746

DO - 10.1080/17588928.2022.2131746

M3 - Article

C2 - 36209434

SN - 1758-8928

VL - 13

SP - 212

EP - 214

JO - Cognitive Neuroscience

JF - Cognitive Neuroscience

ER -