Importance of Resolving Fungal Nomenclature: The Case of Multiple Pathogenic Species in the Cryptococcus Genus

Ferry Hagen; H. Thorsten Lumbsch; Valentina Arsic Arsenijevic; Hamid Badali; Sebastien Bertout; Blake Robert Billmyre; Maria Bragulat; F Javier Cabañes; Mauricio Carbia; Arunaloke Chakrabarti; Sudha Chaturvedi; Vishnu Chaturvedi; Min Chen; Anuradha Chowdhary; María Colom Valiente; Oliver Cornely; Pedro W Crous; Maria S Cuétara; Mara R Diaz; Paul E Verweij

doi:10.1128/mSphere.00238-17

Importance of Resolving Fungal Nomenclature: The Case of Multiple Pathogenic Species in the Cryptococcus Genus

Ferry Hagen, H. Thorsten Lumbsch, Valentina Arsic Arsenijevic, Hamid Badali, Sebastien Bertout, Blake Robert Billmyre, Maria Bragulat, F Javier Cabañes, Mauricio Carbia, Arunaloke Chakrabarti, Sudha Chaturvedi, Vishnu Chaturvedi, Min Chen, Anuradha Chowdhary, María Colom Valiente, Oliver Cornely, Pedro W Crous, Maria S Cuétara, Mara R Diaz, Paul E Verweij

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

113 Citaten (Scopus)

Samenvatting

Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and Cryptococcus neoformans species complexes. After more than 15 years of molecular genetic and phenotypic studies and much debate, a proposal for a taxonomic revision was made. The two varieties within C. neoformans were raised to species level, and the same was done for five genotypes within C. gattii. In a recent perspective (K. J. Kwon-Chung et al., mSphere 2:e00357-16, 2017, https://doi.org/10.1128/mSphere.00357-16), it was argued that this taxonomic proposal was premature and without consensus in the community. Although the authors of the perspective recognized the existence of genetic diversity, they preferred the use of the informal nomenclature “C. neoformans species complex” and “C. gattii species complex.” Here we highlight the advantage of recognizing these seven species, as ignoring these species will impede deciphering further biologically and clinically relevant differences between them, which may in turn delay future clinical advances.

Originele taal-2	Niet gedefinieerd
Tijdschrift	mSphere
Volume	2
DOI's	https://doi.org/10.1128/mSphere.00238-17
Status	Gepubliceerd - 01 aug. 2017

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10.1128/mSphere.00238-17Licentie: CC BY

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Hagen, F., Lumbsch, H. T., Arsic Arsenijevic, V., Badali, H., Bertout, S., Billmyre, B. R., Bragulat, M., Javier Cabañes, F., Carbia, M., Chakrabarti, A., Chaturvedi, S., Chaturvedi, V., Chen, M., Chowdhary, A., Colom Valiente, M., Cornely, O., Crous, P. W., S Cuétara, M., R Diaz, M., & Verweij, P. E. (2017). Importance of Resolving Fungal Nomenclature: The Case of Multiple Pathogenic Species in the Cryptococcus Genus. mSphere, 2. https://doi.org/10.1128/mSphere.00238-17

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title = "Importance of Resolving Fungal Nomenclature: The Case of Multiple Pathogenic Species in the Cryptococcus Genus",

abstract = "Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and Cryptococcus neoformans species complexes. After more than 15 years of molecular genetic and phenotypic studies and much debate, a proposal for a taxonomic revision was made. The two varieties within C. neoformans were raised to species level, and the same was done for five genotypes within C. gattii. In a recent perspective (K. J. Kwon-Chung et al., mSphere 2:e00357-16, 2017, https://doi.org/10.1128/mSphere.00357-16), it was argued that this taxonomic proposal was premature and without consensus in the community. Although the authors of the perspective recognized the existence of genetic diversity, they preferred the use of the informal nomenclature “C. neoformans species complex” and “C. gattii species complex.” Here we highlight the advantage of recognizing these seven species, as ignoring these species will impede deciphering further biologically and clinically relevant differences between them, which may in turn delay future clinical advances.",

author = "Ferry Hagen and Lumbsch, {H. Thorsten} and {Arsic Arsenijevic}, Valentina and Hamid Badali and Sebastien Bertout and Billmyre, {Blake Robert} and Maria Bragulat and {Javier Caba{\~n}es}, F and Mauricio Carbia and Arunaloke Chakrabarti and Sudha Chaturvedi and Vishnu Chaturvedi and Min Chen and Anuradha Chowdhary and {Colom Valiente}, Mar{\'i}a and Oliver Cornely and Crous, {Pedro W} and {S Cu{\'e}tara}, Maria and {R Diaz}, Mara and Verweij, {Paul E}",

year = "2017",

month = aug,

day = "1",

doi = "10.1128/mSphere.00238-17",

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Hagen, F, Lumbsch, HT, Arsic Arsenijevic, V, Badali, H, Bertout, S, Billmyre, BR, Bragulat, M, Javier Cabañes, F, Carbia, M, Chakrabarti, A, Chaturvedi, S, Chaturvedi, V, Chen, M, Chowdhary, A, Colom Valiente, M, Cornely, O, Crous, PW, S Cuétara, M, R Diaz, M & Verweij, PE 2017, 'Importance of Resolving Fungal Nomenclature: The Case of Multiple Pathogenic Species in the Cryptococcus Genus', mSphere, vol. 2. https://doi.org/10.1128/mSphere.00238-17

TY - JOUR

T1 - Importance of Resolving Fungal Nomenclature

T2 - The Case of Multiple Pathogenic Species in the Cryptococcus Genus

AU - Hagen, Ferry

AU - Lumbsch, H. Thorsten

AU - Arsic Arsenijevic, Valentina

AU - Badali, Hamid

AU - Bertout, Sebastien

AU - Billmyre, Blake Robert

AU - Bragulat, Maria

AU - Javier Cabañes, F

AU - Carbia, Mauricio

AU - Chakrabarti, Arunaloke

AU - Chaturvedi, Sudha

AU - Chaturvedi, Vishnu

AU - Chen, Min

AU - Chowdhary, Anuradha

AU - Colom Valiente, María

AU - Cornely, Oliver

AU - Crous, Pedro W

AU - S Cuétara, Maria

AU - R Diaz, Mara

AU - Verweij, Paul E

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and Cryptococcus neoformans species complexes. After more than 15 years of molecular genetic and phenotypic studies and much debate, a proposal for a taxonomic revision was made. The two varieties within C. neoformans were raised to species level, and the same was done for five genotypes within C. gattii. In a recent perspective (K. J. Kwon-Chung et al., mSphere 2:e00357-16, 2017, https://doi.org/10.1128/mSphere.00357-16), it was argued that this taxonomic proposal was premature and without consensus in the community. Although the authors of the perspective recognized the existence of genetic diversity, they preferred the use of the informal nomenclature “C. neoformans species complex” and “C. gattii species complex.” Here we highlight the advantage of recognizing these seven species, as ignoring these species will impede deciphering further biologically and clinically relevant differences between them, which may in turn delay future clinical advances.

AB - Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and Cryptococcus neoformans species complexes. After more than 15 years of molecular genetic and phenotypic studies and much debate, a proposal for a taxonomic revision was made. The two varieties within C. neoformans were raised to species level, and the same was done for five genotypes within C. gattii. In a recent perspective (K. J. Kwon-Chung et al., mSphere 2:e00357-16, 2017, https://doi.org/10.1128/mSphere.00357-16), it was argued that this taxonomic proposal was premature and without consensus in the community. Although the authors of the perspective recognized the existence of genetic diversity, they preferred the use of the informal nomenclature “C. neoformans species complex” and “C. gattii species complex.” Here we highlight the advantage of recognizing these seven species, as ignoring these species will impede deciphering further biologically and clinically relevant differences between them, which may in turn delay future clinical advances.

U2 - 10.1128/mSphere.00238-17

DO - 10.1128/mSphere.00238-17

M3 - Artikel

SN - 2379-5042

VL - 2

JO - mSphere

JF - mSphere

ER -