Insomnia disorder subtypes derived from life history and traits of affect and personality.

TY - JOUR

T1 - Insomnia disorder subtypes derived from life history and traits of affect and personality.

AU - Blanken, T.F.

AU - Benjamins, Jeroen S

AU - Borsboom, Denny

AU - Vermunt, Jeroen K.

AU - Paquola, Casey

AU - Ramautar, Jennifer R

AU - Dekker, Kim

AU - Stoffers, D.

AU - Wassing, Rick

AU - Wei, Yishul

AU - van Someren, E.J.W.

PY - 2019/1/8

Y1 - 2019/1/8

N2 - Insomnia disorder is the second most prevalent mental disorder, and it is a primary risk factor for depression. Inconsistent clinical and biomarker findings in patients with insomnia disorder suggest that heterogeneity exists and that subtypes of this disease remain unrecognised. Previous top-down proposed subtypes in nosologieshave had insufficient validity. In this large-scale study, we aimed to reveal robust subtypes of insomnia disorder by use of data-driven analyses on a multidimensional set of biologically based traits.

AB - Insomnia disorder is the second most prevalent mental disorder, and it is a primary risk factor for depression. Inconsistent clinical and biomarker findings in patients with insomnia disorder suggest that heterogeneity exists and that subtypes of this disease remain unrecognised. Previous top-down proposed subtypes in nosologieshave had insufficient validity. In this large-scale study, we aimed to reveal robust subtypes of insomnia disorder by use of data-driven analyses on a multidimensional set of biologically based traits.

U2 - 10.1016/S2215-0366(18)30464-4

DO - 10.1016/S2215-0366(18)30464-4

M3 - Article

SN - 2215-0366

VL - 6

SP - 151

EP - 163

JO - The Lancet Psychiatry

JF - The Lancet Psychiatry

ER -