Samenvatting
The Hippo signaling pathway exerts a growth-suppressive effect by inhibitory phosphorylation of the oncogenic transcription co-activator Yki/YAP. A recent study paradoxically reports that genetic removal of YAP enhances intestinal stem cell expansion and regeneration.
Originele taal-2 | Engels |
---|---|
Pagina's (van-tot) | 110-112 |
Tijdschrift | Current Biology |
Volume | 23 |
Nummer van het tijdschrift | 3 |
DOI's | |
Status | Gepubliceerd - 2013 |