JMM Profile: Trichosporon yeasts: from superficial pathogen to threat for haematological-neutropenic patients

TY - JOUR

T1 - JMM Profile

T2 - Trichosporon yeasts: from superficial pathogen to threat for haematological-neutropenic patients

AU - Francisco, Elaine Cristina

AU - Hagen, Ferry

PY - 2022/12

Y1 - 2022/12

N2 - Trichosporon yeasts are classical agents of superficial mycoses, and they are ranked as the first to second predominant basidiomycetous yeast able to cause invasive infections. The clinical presentation of Trichosporon infections varies with the affected anatomical site, with fungaemia present in the majority of invasive trichosporonosis cases. Only a limited number of antifungal compounds can be used to treat Trichosporon infections. Azoles are the first choice due to their intrinsic resistance to echinocandins. Better laboratory methods and up-to-date databases of commercial platforms are required to improve identification, susceptibility testing and surveillance of this potentially threating infection.

AB - Trichosporon yeasts are classical agents of superficial mycoses, and they are ranked as the first to second predominant basidiomycetous yeast able to cause invasive infections. The clinical presentation of Trichosporon infections varies with the affected anatomical site, with fungaemia present in the majority of invasive trichosporonosis cases. Only a limited number of antifungal compounds can be used to treat Trichosporon infections. Azoles are the first choice due to their intrinsic resistance to echinocandins. Better laboratory methods and up-to-date databases of commercial platforms are required to improve identification, susceptibility testing and surveillance of this potentially threating infection.

U2 - 10.1099/jmm.0.001621

DO - 10.1099/jmm.0.001621

M3 - Article

C2 - 36748684

SN - 0022-2615

VL - 71

JO - Journal of Medical Microbiology

JF - Journal of Medical Microbiology

IS - 12

ER -