KRS: A cut away from release in exosomes

Catherine Rabouille

doi:10.1083/jcb.201706039

KRS: A cut away from release in exosomes

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

5 Citaten (Scopus)

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Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.

Originele taal-2	Engels
Pagina's (van-tot)	1891-1893
Aantal pagina's	3
Tijdschrift	Journal of Cell Biology
Volume	216
Nummer van het tijdschrift	7
DOI's	https://doi.org/10.1083/jcb.201706039
Status	Gepubliceerd - 03 jul. 2017

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title = "KRS: A cut away from release in exosomes",

abstract = "Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.",

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KW - Exosomes

KW - Humans

KW - Lysine-tRNA Ligase

KW - Journal Article

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DO - 10.1083/jcb.201706039

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KRS: A cut away from release in exosomes

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