Major construction entails major demolition

TY - JOUR

T1 - Major construction entails major demolition

AU - Korotkevich, Ekaterina

AU - Hiiragi, Takashi

N1 - Copyright © 2022 Elsevier Inc. All rights reserved.

PY - 2022/6/6

Y1 - 2022/6/6

N2 - Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.

AB - Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.

KW - Animals

KW - Dynamins

KW - Mice

KW - Mitochondrial Dynamics

KW - Mitochondrial Proteins

KW - Mitophagy

U2 - 10.1016/j.devcel.2022.05.008

DO - 10.1016/j.devcel.2022.05.008

M3 - Article

C2 - 35671703

SN - 1534-5807

VL - 57

SP - 1311

EP - 1313

JO - Developmental Cell

JF - Developmental Cell

IS - 11

ER -