TY - JOUR
T1 - Malassezia spp. Yeasts of Emerging Concern in Fungemia
AU - Rhimi, Wafa
AU - Theelen, Bart
AU - Boekhout, Teun
AU - Otranto, Domenico
AU - Cafarchia, Claudia
N1 - Copyright © 2020 Rhimi, Theelen, Boekhout, Otranto and Cafarchia.
PY - 2020/7/28
Y1 - 2020/7/28
N2 - Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.
AB - Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.
U2 - 10.3389/fcimb.2020.00370
DO - 10.3389/fcimb.2020.00370
M3 - Book/Film/Article review
C2 - 32850475
SN - 2235-2988
VL - 10
SP - 370
JO - Frontiers in cellular and infection microbiology
JF - Frontiers in cellular and infection microbiology
ER -