Mechanotransduction: vinculin provides stability when tension rises

E. Spanjaard; J. de Rooij

doi:10.1016/j.cub.2013.01.020

Mechanotransduction: vinculin provides stability when tension rises

E. Spanjaard, J. de Rooij

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

Samenvatting

By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.

Originele taal-2	Engels
Pagina's (van-tot)	159-161
Tijdschrift	Current Biology
Volume	23
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.cub.2013.01.020
Status	Gepubliceerd - 2013

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10.1016/j.cub.2013.01.020

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title = "Mechanotransduction: vinculin provides stability when tension rises",

abstract = "By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.",

author = "E. Spanjaard and {de Rooij}, J.",

note = "Reporting year: 2013",

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DO - 10.1016/j.cub.2013.01.020

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Mechanotransduction: vinculin provides stability when tension rises

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