MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

Sander P J Joosten; Tomohiro Mizutani; Marcel Spaargaren; Hans Clevers; Steven T Pals

doi:10.1053/j.gastro.2019.06.029

MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

Sander P J Joosten, Tomohiro Mizutani, Marcel Spaargaren, Hans Clevers, Steven T Pals

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

13 Citaten (Scopus)

Originele taal-2	Engels
Pagina's (van-tot)	1153-1155.e1
Tijdschrift	Gastroenterology
Volume	157
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1053/j.gastro.2019.06.029
Status	Gepubliceerd - okt. 2019

Toegang tot document

10.1053/j.gastro.2019.06.029

Citeer dit

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title = "MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance",

keywords = "Antineoplastic Agents/pharmacology, Cell Line, Tumor, Cell Proliferation/drug effects, Colorectal Neoplasms/drug therapy, Drug Resistance, Neoplasm/drug effects, ErbB Receptors/antagonists & inhibitors, Gefitinib/pharmacology, Genes, APC, Humans, Intestinal Mucosa/drug effects, Mutation, Neoplastic Stem Cells/drug effects, Protein Kinase Inhibitors/pharmacology, Proto-Oncogene Proteins c-met/antagonists & inhibitors, Pyrazines/pharmacology, Signal Transduction, Triazines/pharmacology",

author = "Joosten, {Sander P J} and Tomohiro Mizutani and Marcel Spaargaren and Hans Clevers and Pals, {Steven T}",

year = "2019",

month = oct,

doi = "10.1053/j.gastro.2019.06.029",

language = "English",

volume = "157",

pages = "1153--1155.e1",

journal = "Gastroenterology",

issn = "0016-5085",

publisher = "W.B. Saunders Ltd",

number = "4",

}

MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance. / Joosten, Sander P J; Mizutani, Tomohiro; Spaargaren, Marcel et al.
In: Gastroenterology, Vol. 157, Nr. 4, 10.2019, blz. 1153-1155.e1.

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

TY - JOUR

T1 - MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

AU - Joosten, Sander P J

AU - Mizutani, Tomohiro

AU - Spaargaren, Marcel

AU - Clevers, Hans

AU - Pals, Steven T

PY - 2019/10

Y1 - 2019/10

KW - Antineoplastic Agents/pharmacology

KW - Cell Line, Tumor

KW - Cell Proliferation/drug effects

KW - Colorectal Neoplasms/drug therapy

KW - Drug Resistance, Neoplasm/drug effects

KW - ErbB Receptors/antagonists & inhibitors

KW - Gefitinib/pharmacology

KW - Genes, APC

KW - Humans

KW - Intestinal Mucosa/drug effects

KW - Mutation

KW - Neoplastic Stem Cells/drug effects

KW - Protein Kinase Inhibitors/pharmacology

KW - Proto-Oncogene Proteins c-met/antagonists & inhibitors

KW - Pyrazines/pharmacology

KW - Signal Transduction

KW - Triazines/pharmacology

U2 - 10.1053/j.gastro.2019.06.029

DO - 10.1053/j.gastro.2019.06.029

M3 - Article

C2 - 31255653

SN - 0016-5085

VL - 157

SP - 1153-1155.e1

JO - Gastroenterology

JF - Gastroenterology

IS - 4

ER -