Microfluidics as an Emerging Precision Tool in Developmental Biology

TY - JOUR

T1 - Microfluidics as an Emerging Precision Tool in Developmental Biology

AU - Sonnen, Katharina F

AU - Merten, Christoph A

N1 - Copyright © 2019 Elsevier Inc. All rights reserved.

PY - 2019/2/11

Y1 - 2019/2/11

N2 - Microfluidics has become a precision tool in modern biology. It enables omics data to be obtained from individual cells, as compared to averaged signals from cell populations, and it allows manipulation of biological specimens in entirely new ways. Cells and organisms can be perturbed at extraordinary spatiotemporal resolution, revealing mechanistic insights that would otherwise remain hidden. In this perspective article, we discuss the current and future impact of microfluidic technology in the field of developmental biology. In addition, we provide detailed information on how to start using this technology even without prior experience.

AB - Microfluidics has become a precision tool in modern biology. It enables omics data to be obtained from individual cells, as compared to averaged signals from cell populations, and it allows manipulation of biological specimens in entirely new ways. Cells and organisms can be perturbed at extraordinary spatiotemporal resolution, revealing mechanistic insights that would otherwise remain hidden. In this perspective article, we discuss the current and future impact of microfluidic technology in the field of developmental biology. In addition, we provide detailed information on how to start using this technology even without prior experience.

U2 - 10.1016/j.devcel.2019.01.015

DO - 10.1016/j.devcel.2019.01.015

M3 - Article

C2 - 30753835

VL - 48

SP - 293

EP - 311

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 3

ER -