Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets

TY - JOUR

T1 - Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets

AU - Hadavi, Elahe

AU - Leijten, Jeroen

AU - Engelse, Marten

AU - de Koning, Eelco

AU - Jonkheijm, Pascal

AU - Karperien, Marcel

AU - van Apeldoorn, Aart

PY - 2019/2

Y1 - 2019/2

N2 - IMPACT STATEMENT: This research deals with finding a proper bioengineering strategy to improve the outcome of islets transplantation for treatment of type 1 diabetes. It is focused on the mimicking of islet extracellular matrix niche in microwell islet delivery devices to improve their endocrine function.

AB - IMPACT STATEMENT: This research deals with finding a proper bioengineering strategy to improve the outcome of islets transplantation for treatment of type 1 diabetes. It is focused on the mimicking of islet extracellular matrix niche in microwell islet delivery devices to improve their endocrine function.

U2 - 10.1089/ten.TEC.2018.0336

DO - 10.1089/ten.TEC.2018.0336

M3 - Article

C2 - 30632461

SN - 1937-3384

VL - 25

SP - 71

EP - 81

JO - Tissue Engineering - Part C: Methods

JF - Tissue Engineering - Part C: Methods

IS - 2

ER -