Non-traumatic keratitis due to Colletotrichum truncatum

Reina Llamos, Abdullah M S Al-Hatmi, Gerardo Martínez, Ferry Hagen, Rosario Velar, Alexeide de la Caridad Castillo Pérez, Jacques F Meis, María T Illnait-Zaragozí

    Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

    Samenvatting

    INTRODUCTION: The fungal genus Colletotrichum is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation.

    CASE PRESENTATION: We report two cases of keratitis due Colletotrichum truncatum in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25  mg l-1. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome.

    CONCLUSION: C. truncatum caused keratomycosis which did not respond to topical antifungal agents. To the best of our knowledge these are the first reported cases of keratitis due to this fungus in Cuba and Latin-America and highlights the expanding spectrum of fungal agents causing eye infections.

    Originele taal-2Engels
    Pagina's (van-tot)e005047
    TijdschriftJMM Case Reports
    Volume3
    Nummer van het tijdschrift4
    DOI's
    StatusGepubliceerd - aug. 2016

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