Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

Tomohiro Mizutani; Yoshiyuki Tsukamoto; Hans Clevers

doi:10.1083/jcb.201704014

Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

Tomohiro Mizutani, Yoshiyuki Tsukamoto, Hans Clevers

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

2 Citaten (Scopus)

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Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of two-dimensional cell lines, while closely representing the in vivo situation.

Originele taal-2	Engels
Pagina's (van-tot)	1505-1507
Aantal pagina's	3
Tijdschrift	Journal of Cell Biology
Volume	216
Nummer van het tijdschrift	6
DOI's	https://doi.org/10.1083/jcb.201704014
Status	Gepubliceerd - 05 jun. 2017

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title = "Oncogene-inducible organoids as a miniature platform to assess cancer characteristics",

abstract = "Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of two-dimensional cell lines, while closely representing the in vivo situation.",

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AU - Clevers, Hans

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KW - Humans

KW - Mice, Transgenic

KW - Neoplasms

KW - Oncogenes

KW - Organoids

KW - Signal Transduction

KW - Journal Article

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Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

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