Post-influenzal triazole-resistant aspergillosis following allogeneic stem cell transplantation

Alida Fe Talento, Katie Dunne, Niamh Murphy, Brian O'Connell, Grace Chan, Eimear Ann Joyce, Ferry Hagen, Jacques F Meis, Ruairi Fahy, Larry Bacon, Elisabeth Vandenberge, Thomas R Rogers

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review


Influenza virus infection is now recognised as a risk factor for invasive pulmonary aspergillosis (IPA). Delays in diagnosis contribute to delayed commencement of antifungal therapy. In addition, the emergence of resistance to first-line triazole antifungal agents puts emphasis on early detection to prevent adverse outcomes. We present 2 allogeneic stem cell transplant patients who developed IPA due to triazole-resistant Aspergillus fumigatus following influenza infection. We underline the challenges faced in the management of these cases, the importance of early diagnosis and need for surveillance given the emergence of triazole resistance.

Originele taal-2Engels
Pagina's (van-tot)570-575
Aantal pagina's6
Nummer van het tijdschrift8
StatusGepubliceerd - aug. 2018


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