Principles of intensive human neuroimaging

TY - JOUR

T1 - Principles of intensive human neuroimaging

AU - Kupers, Eline R

AU - Knapen, Tomas

AU - Merriam, Elisha P

AU - Kay, Kendrick N

N1 - Copyright © 2024 Elsevier Ltd. All rights reserved.

PY - 2024/10/24

Y1 - 2024/10/24

N2 - The rise of large, publicly shared functional magnetic resonance imaging (fMRI) data sets in human neuroscience has focused on acquiring either a few hours of data on many individuals ('wide' fMRI) or many hours of data on a few individuals ('deep' fMRI). In this opinion article, we highlight an emerging approach within deep fMRI, which we refer to as 'intensive' fMRI: one that strives for extensive sampling of cognitive phenomena to support computational modeling and detailed investigation of brain function at the single voxel level. We discuss the fundamental principles, trade-offs, and practical considerations of intensive fMRI. We also emphasize that intensive fMRI does not simply mean collecting more data: it requires careful design of experiments to enable a rich hypothesis space, optimizing data quality, and strategically curating public resources to maximize community impact.

AB - The rise of large, publicly shared functional magnetic resonance imaging (fMRI) data sets in human neuroscience has focused on acquiring either a few hours of data on many individuals ('wide' fMRI) or many hours of data on a few individuals ('deep' fMRI). In this opinion article, we highlight an emerging approach within deep fMRI, which we refer to as 'intensive' fMRI: one that strives for extensive sampling of cognitive phenomena to support computational modeling and detailed investigation of brain function at the single voxel level. We discuss the fundamental principles, trade-offs, and practical considerations of intensive fMRI. We also emphasize that intensive fMRI does not simply mean collecting more data: it requires careful design of experiments to enable a rich hypothesis space, optimizing data quality, and strategically curating public resources to maximize community impact.

U2 - 10.1016/j.tins.2024.09.011

DO - 10.1016/j.tins.2024.09.011

M3 - Article

C2 - 39455343

SN - 0166-2236

VL - 47

SP - 856

EP - 864

JO - Trends in Neurosciences

JF - Trends in Neurosciences

ER -