Pronouns reactivate conceptual representations in human hippocampal neurons

D E Dijksterhuis; M W Self; J K Possel; J C Peters; E C W van Straaten; S Idema; J C Baaijen; S M A van der Salm; E J Aarnoutse; N C E van Klink; P van Eijsden; S Hanslmayr; R Chelvarajah; F Roux; L D Kolibius; V Sawlani; D T Rollings; S Dehaene; P R Roelfsema

doi:10.1126/science.adr2813

Pronouns reactivate conceptual representations in human hippocampal neurons

D E Dijksterhuis, M W Self, J K Possel, J C Peters, E C W van Straaten, S Idema, J C Baaijen, S M A van der Salm, E J Aarnoutse, N C E van Klink, P van Eijsden, S Hanslmayr, R Chelvarajah, F Roux, L D Kolibius, V Sawlani, D T Rollings, S Dehaene, P R Roelfsema

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

4 Citaten (Scopus)

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During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words. To minimize repetition and utterance length, languages use pronouns, like the word "she," to refer to nouns and phrases that were previously introduced. It has been suggested that language comprehension requires that pronouns activate the same neuronal representations as the nouns themselves. We recorded from individual neurons in the human hippocampus during a reading task. Cells that were selective to a particular noun were later reactivated by pronouns that refer to the cells' preferred noun. These results imply that concept cells contribute to a rapid and dynamic semantic memory network that is recruited during language comprehension.

Originele taal-2	Engels
Pagina's (van-tot)	1478-1484
Aantal pagina's	7
Tijdschrift	Science
Volume	385
Nummer van het tijdschrift	6716
DOI's	https://doi.org/10.1126/science.adr2813
Status	Gepubliceerd - 27 sep. 2024

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Dijksterhuis, D. E., Self, M. W., Possel, J. K., Peters, J. C., van Straaten, E. C. W., Idema, S., Baaijen, J. C., van der Salm, S. M. A., Aarnoutse, E. J., van Klink, N. C. E., van Eijsden, P., Hanslmayr, S., Chelvarajah, R., Roux, F., Kolibius, L. D., Sawlani, V., Rollings, D. T., Dehaene, S., & Roelfsema, P. R. (2024). Pronouns reactivate conceptual representations in human hippocampal neurons. Science, 385(6716), 1478-1484. https://doi.org/10.1126/science.adr2813

@article{3008c71b10cd480f9fb7cd7fb7080822,

title = "Pronouns reactivate conceptual representations in human hippocampal neurons",

abstract = "During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words. To minimize repetition and utterance length, languages use pronouns, like the word {"}she,{"} to refer to nouns and phrases that were previously introduced. It has been suggested that language comprehension requires that pronouns activate the same neuronal representations as the nouns themselves. We recorded from individual neurons in the human hippocampus during a reading task. Cells that were selective to a particular noun were later reactivated by pronouns that refer to the cells' preferred noun. These results imply that concept cells contribute to a rapid and dynamic semantic memory network that is recruited during language comprehension.",

keywords = "Humans, Neurons/physiology, Hippocampus/physiology, Reading, Comprehension, Male, Female, Language, Semantics, Memory/physiology, Adult",

author = "Dijksterhuis, {D E} and Self, {M W} and Possel, {J K} and Peters, {J C} and {van Straaten}, {E C W} and S Idema and Baaijen, {J C} and {van der Salm}, {S M A} and Aarnoutse, {E J} and {van Klink}, {N C E} and {van Eijsden}, P and S Hanslmayr and R Chelvarajah and F Roux and Kolibius, {L D} and V Sawlani and Rollings, {D T} and S Dehaene and Roelfsema, {P R}",

year = "2024",

month = sep,

day = "27",

doi = "10.1126/science.adr2813",

language = "English",

volume = "385",

pages = "1478--1484",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science (AAAS)",

number = "6716",

}

Dijksterhuis, DE, Self, MW, Possel, JK, Peters, JC, van Straaten, ECW, Idema, S, Baaijen, JC, van der Salm, SMA, Aarnoutse, EJ, van Klink, NCE, van Eijsden, P, Hanslmayr, S, Chelvarajah, R, Roux, F, Kolibius, LD, Sawlani, V, Rollings, DT, Dehaene, S & Roelfsema, PR 2024, 'Pronouns reactivate conceptual representations in human hippocampal neurons', Science, vol. 385, nr. 6716, blz. 1478-1484. https://doi.org/10.1126/science.adr2813

TY - JOUR

T1 - Pronouns reactivate conceptual representations in human hippocampal neurons

AU - Dijksterhuis, D E

AU - Self, M W

AU - Possel, J K

AU - Peters, J C

AU - van Straaten, E C W

AU - Idema, S

AU - Baaijen, J C

AU - van der Salm, S M A

AU - Aarnoutse, E J

AU - van Klink, N C E

AU - van Eijsden, P

AU - Hanslmayr, S

AU - Chelvarajah, R

AU - Roux, F

AU - Kolibius, L D

AU - Sawlani, V

AU - Rollings, D T

AU - Dehaene, S

AU - Roelfsema, P R

PY - 2024/9/27

Y1 - 2024/9/27

N2 - During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words. To minimize repetition and utterance length, languages use pronouns, like the word "she," to refer to nouns and phrases that were previously introduced. It has been suggested that language comprehension requires that pronouns activate the same neuronal representations as the nouns themselves. We recorded from individual neurons in the human hippocampus during a reading task. Cells that were selective to a particular noun were later reactivated by pronouns that refer to the cells' preferred noun. These results imply that concept cells contribute to a rapid and dynamic semantic memory network that is recruited during language comprehension.

AB - During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words. To minimize repetition and utterance length, languages use pronouns, like the word "she," to refer to nouns and phrases that were previously introduced. It has been suggested that language comprehension requires that pronouns activate the same neuronal representations as the nouns themselves. We recorded from individual neurons in the human hippocampus during a reading task. Cells that were selective to a particular noun were later reactivated by pronouns that refer to the cells' preferred noun. These results imply that concept cells contribute to a rapid and dynamic semantic memory network that is recruited during language comprehension.

KW - Humans

KW - Neurons/physiology

KW - Hippocampus/physiology

KW - Reading

KW - Comprehension

KW - Male

KW - Female

KW - Language

KW - Semantics

KW - Memory/physiology

KW - Adult

U2 - 10.1126/science.adr2813

DO - 10.1126/science.adr2813

M3 - Article

C2 - 39325896

SN - 0036-8075

VL - 385

SP - 1478

EP - 1484

JO - Science

JF - Science

IS - 6716

ER -

Pronouns reactivate conceptual representations in human hippocampal neurons

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