Retriever fetches integrins from endosomes

Catherine Rabouille

doi:10.1038/ncb3612

Retriever fetches integrins from endosomes

Catherine Rabouille

Hubrecht Institute

Hubrecht Institute/KNAW and UMC Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands; and the Department of Cell Biology, UMC Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

6 Citaten (Scopus)

Samenvatting

Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α5β1 integrins.

Originele taal-2	Engels
Pagina's (van-tot)	1144-1146
Aantal pagina's	3
Tijdschrift	Nature Cell Biology
Volume	19
Nummer van het tijdschrift	10
DOI's	https://doi.org/10.1038/ncb3612
Status	Gepubliceerd - 29 sep. 2017

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10.1038/ncb3612

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abstract = "Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α5β1 integrins.",

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KW - Cell Membrane

KW - Endosomes

KW - Humans

KW - Integrins

KW - Protein Transport

KW - Sorting Nexins

KW - Journal Article

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Retriever fetches integrins from endosomes

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