Structural variants in the great tit genome and their effect on seasonal timing

V.H. da Silva

doi:10.18174/512907

Structural variants in the great tit genome and their effect on seasonal timing

V.H. da Silva

NIOO - Animal Ecology (AnE)

Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

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The great tit (Parus major) is a songbird that has been extensively explored in ecological and evolutionary studies, shedding light on the effects of the global warming on nature. Genomic structural variability was never explored in detail in these species. The aim of this thesis was to detect, map, characterize and associate, with seasonal timing, structural variants that are present in the great tit genome such as copy number variations (CNVs) and inversions. First, this thesis presents a genome-wide map of CNV regions in the great tit genome, showing how these variants are associated with genomic architecture underlying their molecular formation. Second, CNVs were associated with breeding timing. Finally, this thesis investigate the genomic complexity of a large inversion in the Chromosome 1A. The inversion is recessive lethal and is inherited twice more than expected from male carriers but are normally inherited from female carriers, suggesting a selfish gene.

Originele taal-2	Engels
Toekennende instantie	Wageningen University
Begeleider(s)/adviseur	Groenen, Martien A.M. , Promotor, Externe Persoon Visser, Marcel E., Promotor Crooijmans, Richard P.M.A, Co-promotor, Externe Persoon Johansson, Anna M., Promotor, Externe Persoon
Datum van toekenning	24 jan. 2020
DOI's	https://doi.org/10.18174/512907
Status	Gepubliceerd - 2020

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title = "Structural variants in the great tit genome and their effect on seasonal timing",

abstract = "The great tit (Parus major) is a songbird that has been extensively explored in ecological and evolutionary studies, shedding light on the effects of the global warming on nature. Genomic structural variability was never explored in detail in these species. The aim of this thesis was to detect, map, characterize and associate, with seasonal timing, structural variants that are present in the great tit genome such as copy number variations (CNVs) and inversions. First, this thesis presents a genome-wide map of CNV regions in the great tit genome, showing how these variants are associated with genomic architecture underlying their molecular formation. Second, CNVs were associated with breeding timing. Finally, this thesis investigate the genomic complexity of a large inversion in the Chromosome 1A. The inversion is recessive lethal and is inherited twice more than expected from male carriers but are normally inherited from female carriers, suggesting a selfish gene.",

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year = "2020",

doi = "10.18174/512907",

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type = "PhD thesis",

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AB - The great tit (Parus major) is a songbird that has been extensively explored in ecological and evolutionary studies, shedding light on the effects of the global warming on nature. Genomic structural variability was never explored in detail in these species. The aim of this thesis was to detect, map, characterize and associate, with seasonal timing, structural variants that are present in the great tit genome such as copy number variations (CNVs) and inversions. First, this thesis presents a genome-wide map of CNV regions in the great tit genome, showing how these variants are associated with genomic architecture underlying their molecular formation. Second, CNVs were associated with breeding timing. Finally, this thesis investigate the genomic complexity of a large inversion in the Chromosome 1A. The inversion is recessive lethal and is inherited twice more than expected from male carriers but are normally inherited from female carriers, suggesting a selfish gene.

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DO - 10.18174/512907

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ER -

Structural variants in the great tit genome and their effect on seasonal timing

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