Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora

TY - JOUR

T1 - Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora

AU - Najafzadeh, M.J.

AU - Rezusta, A.

AU - Cameo, M.I.

AU - Zubiri, M.L.

AU - Yus, M.C.

AU - Badali, H.

AU - Revillo, M.J.

AU - de Hoog, G.S.

N1 - Reporting year: 2010

PY - 2010

Y1 - 2010

N2 - We report a case of chromoblastomycosis in a 67-year-old female farmer, which involved a large (20 x 30 cm) cicatricial erythematous plaque on the inner side of her right thigh. The lesion was initially a small nodule which gradually extended over 36 years. Direct microscopic examination revealed a granulomatous lesion with muriform cells surrounded by giant cells. The mould recovered in cultures was dark olivaceous and identified as Fonsecaea monophora by ribosomal internal transcribe spacer (ITS) sequence data. The lesion was successfully cured after 4 months treatment with itraconazole, but there was a relapse.

AB - We report a case of chromoblastomycosis in a 67-year-old female farmer, which involved a large (20 x 30 cm) cicatricial erythematous plaque on the inner side of her right thigh. The lesion was initially a small nodule which gradually extended over 36 years. Direct microscopic examination revealed a granulomatous lesion with muriform cells surrounded by giant cells. The mould recovered in cultures was dark olivaceous and identified as Fonsecaea monophora by ribosomal internal transcribe spacer (ITS) sequence data. The lesion was successfully cured after 4 months treatment with itraconazole, but there was a relapse.

U2 - 10.3109/13693780903008813

DO - 10.3109/13693780903008813

M3 - Article

VL - 48

SP - 390

EP - 393

JO - Medical Mycology

JF - Medical Mycology

SN - 1369-3786

IS - 2

ER -