Samenvatting
What you see is what you get-imaging techniques have long been essential for visualization and understanding of tissue development, homeostasis, and regeneration, which are driven by stem cell self-renewal and differentiation. Advances in molecular and tissue modeling techniques in the last decade are providing new imaging modalities to explore tissue heterogeneity and plasticity. Here we describe current state-of-the-art imaging modalities for tissue research at multiple scales, with a focus on explaining key tradeoffs such as spatial resolution, penetration depth, capture time/frequency, and moieties. We explore emerging tissue modeling and molecular tools that improve resolution, specificity, and throughput.
Originele taal-2 | Engels |
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Pagina's (van-tot) | 603-622 |
Aantal pagina's | 20 |
Tijdschrift | Cell Stem Cell |
Volume | 28 |
Nummer van het tijdschrift | 4 |
DOI's | |
Status | Gepubliceerd - 01 apr. 2021 |