The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan

TY - JOUR

T1 - The Upper Hand of the Otu Amyloid Fibers

T2 - Increasing Enzymatic Activity and Prolonging Lifespan

AU - Rabouille, Catherine

N1 - Copyright © 2019 Elsevier Inc. All rights reserved.

PY - 2019/4/18

Y1 - 2019/4/18

N2 - The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.

AB - The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.

U2 - 10.1016/j.molcel.2019.03.038

DO - 10.1016/j.molcel.2019.03.038

M3 - Article

C2 - 31002803

SN - 1097-2765

VL - 74

SP - 225

EP - 226

JO - Molecular Cell

JF - Molecular Cell

IS - 2

ER -