Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

F. De Laender, D.J. Van Oevelen, J.J. Middelburg, K.E.R. Soetaert

    Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

    Samenvatting

    Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies
    Originele taal-2Engels
    Pagina's (van-tot)240-246
    TijdschriftEcotoxicology and Environmental Safety
    Volume73
    Nummer van het tijdschrift3
    DOI's
    StatusGepubliceerd - 2010

    Vingerafdruk

    Duik in de onderzoeksthema's van 'Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients'. Samen vormen ze een unieke vingerafdruk.

    Citeer dit