Virulence markers of opportunistic black yeast in Exophiala

Hafize Sav, Fatma Ozakkas, Rabiye Altınbas, Nuri Kiraz, Ayşegül Tümgör, Ramazan Gümral, Aylin Döğen, Macit Ilkit, G Sybren de Hoog

    Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

    Samenvatting

    The black yeast genus Exophiala is known to cause a wide variety of diseases in severely ill individuals but can also affect immunocompetent individuals. Virulence markers and other physiological parameters were tested in eight clinical and 218 environmental strains, with a specific focus on human-dominated habitats for the latter. Urease and catalase were consistently present in all samples; four strains expressed proteinase and three strains expressed DNase, whereas none of the strains showed phospholipase, haemolysis, or co-haemolysis activities. Biofilm formation was identified in 30 (13.8%) of the environmental isolates, particularly in strains from dishwashers, and was noted in only two (25%) of the clinical strains. These results indicate that virulence factors are inconsistently present in the investigated Exophiala species, suggesting opportunism rather than pathogenicity.

    Originele taal-2Engels
    Pagina's (van-tot)343-50
    Aantal pagina's8
    TijdschriftMycoses
    Volume59
    Nummer van het tijdschrift6
    DOI's
    StatusGepubliceerd - jun 2016

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