Visualizing the Human Subcortex Using Ultra-high Field Magnetic Resonance Imaging

TY - JOUR

T1 - Visualizing the Human Subcortex Using Ultra-high Field Magnetic Resonance Imaging

AU - Keuken, Max C

AU - Isaacs, Bethany R

AU - Trampel, Robert

AU - van der Zwaag, W

AU - Forstmann, B U

PY - 2018

Y1 - 2018

N2 - With the recent increased availability of ultra-high field (UHF) magnetic resonance imaging (MRI), substantial progress has been made in visualizing the human brain, which can now be done in extraordinary detail. This review provides an extensive overview of the use of UHF MRI in visualizing the human subcortex for both healthy and patient populations. The high inter-subject variability in size and location of subcortical structures limits the usability of atlases in the midbrain. Fortunately, the combined results of this review indicate that a large number of subcortical areas can be visualized in individual space using UHF MRI. Current limitations and potential solutions of UHF MRI for visualizing the subcortex are also discussed.

AB - With the recent increased availability of ultra-high field (UHF) magnetic resonance imaging (MRI), substantial progress has been made in visualizing the human brain, which can now be done in extraordinary detail. This review provides an extensive overview of the use of UHF MRI in visualizing the human subcortex for both healthy and patient populations. The high inter-subject variability in size and location of subcortical structures limits the usability of atlases in the midbrain. Fortunately, the combined results of this review indicate that a large number of subcortical areas can be visualized in individual space using UHF MRI. Current limitations and potential solutions of UHF MRI for visualizing the subcortex are also discussed.

KW - Journal Article

KW - Review

U2 - 10.1007/s10548-018-0638-7

DO - 10.1007/s10548-018-0638-7

M3 - Article

C2 - 29497874

SN - 0896-0267

VL - 31

SP - 513

EP - 545

JO - Brain Topography

JF - Brain Topography

ER -